[Pt(O,O′-acac)(γ-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway

BACKGROUND AND PURPOSE: We showed previously that a new Pt complex containing an O,O′-chelated acetylacetonate ligand (acac) and a dimethylsulphide in the Pt coordination sphere, [Pt(O,O′-acac)(γ-acac)(DMS)], induces apoptosis in HeLa cells. The objective of this study was to investigate the hypothe...

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Autores principales: Muscella, A, Calabriso, N, Fanizzi, F P, De Pascali, S A, Urso, L, Ciccarese, A, Migoni, D, Marsigliante, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199379/
https://ncbi.nlm.nih.gov/pubmed/18026127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707576
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