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[Pt(O,O′-acac)(γ-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway
BACKGROUND AND PURPOSE: We showed previously that a new Pt complex containing an O,O′-chelated acetylacetonate ligand (acac) and a dimethylsulphide in the Pt coordination sphere, [Pt(O,O′-acac)(γ-acac)(DMS)], induces apoptosis in HeLa cells. The objective of this study was to investigate the hypothe...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199379/ https://ncbi.nlm.nih.gov/pubmed/18026127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707576 |
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