USP2a alters chemotherapeutic response by modulating redox

Cancer cells are characterized by altered ubiquitination of many proteins. The ubiquitin-specific protease 2a (USP2a) is a deubiquitinating enzyme overexpressed in prostate adenocarcinomas, where it exhibits oncogenic behavior in a variety of ways including targeting c-Myc via the miR-34b/c cluster....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Benassi, B, Marani, M, Loda, M, Blandino, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789164/
https://ncbi.nlm.nih.gov/pubmed/24071644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.289
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