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MYC Is Activated by USP2a-Mediated Modulation of MicroRNAs in Prostate Cancer
Ubiquitin-specific protease 2a (USP2a) is overexpressed in almost half of human prostate cancers and c-Myc is amplified in one third of these tumor types. Transgenic MYC expression drives invasive adenocarcinomas in the murine prostate. We show that overexpression of USP2a downregulates a set of mic...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523361/ https://ncbi.nlm.nih.gov/pubmed/22585994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0219 |
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