Identification of a candidate therapeutic autophagy–inducing peptide

The lysosomal degradation pathway of autophagy has a crucial role in defence against infection, neurodegenerative disorders, cancer and ageing. Accordingly, agents that induce autophagy may have broad therapeutic applications. One approach to developing such agents is to exploit autophagy manipulati...

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Main Authors: Shoji-Kawata, Sanae, Sumpter, Rhea, Leveno, Matthew, Campbell, Grant R., Zou, Zhongju, Kinch, Lisa, Wilkins, Angela D., Sun, Qihua, Pallauf, Kathrin, MacDuff, Donna, Huerta, Carlos, Virgin, Herbert W., Helms, J. Bernd, Eerland, Ruud, Tooze, Sharon A., Xavier, Ramnik, Lenschow, Deborah J., Yamamoto, Ai, King, David, Lichtarge, Olivier, Grishin, Nick V., Spector, Stephen A., Kaloyanova, Dora V., Levine, Beth
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788641/
https://ncbi.nlm.nih.gov/pubmed/23364696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11866
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