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Identification of long-lived proteins reveals exceptional stability of essential cellular structures

Intracellular proteins with long lifespans have recently been linked to age-dependent defects, ranging from decreased fertility to the functional decline of neurons. Why long-lived proteins exist in metabolically active cellular environments and how they are maintained over time remains poorly under...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Toyama, Brandon H., Savas, Jeffrey N., Park, Sung Kyu, Harris, Michael S., Ingolia, Nicholas T., Yates, John R., Hetzer, Martin W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788602/
https://ncbi.nlm.nih.gov/pubmed/23993091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.037
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