PS3-35: MRI Detection of Substantia Nigra Degeneration in Parkinson’s Disease: Developing a Candidate Biomarker

BACKGROUND/AIMS: The substantia nigra (SN) selectively degenerates in Parkinson’s disease (PD). Prior MRI studies of SN have used manual segmentation to make quantitative measurements, an approach with inherently limited accuracy. Here we used an in-house optimized neuromelanin MRI (NM-MRI) protocol...

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Autors principals: Huddleston, Daniel, Chen, Xiangchuan, Langley, Jason, Hu, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: Marshfield Clinic 2013
Matèries:
Selected Abstracts-HMORN 2013: Chronic Conditions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3121/cmr.2013.1176.ps3-35
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