Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinson's disease

BACKGROUND: To date there are no validated MRI biomarkers to assist diagnosis of Parkinson’s disease (PD). Our aim was to investigate PD related iron changes in the substantia nigra pars compacta (SNpc) as defined by neuromelanin-sensitive MR contrast. METHODS: Thirty-nine PD participants and 33 hea...

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Detalles Bibliográficos
Publicado en:Neuroimage Clin
Main Authors: He, Naying, Langley, Jason, Huddleston, Daniel E., Chen, Shengdi, Huang, Pei, Ling, Huawei, Yan, Fuhua, Hu, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479276/
https://ncbi.nlm.nih.gov/pubmed/32889398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102391
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