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Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinson's disease

BACKGROUND: To date there are no validated MRI biomarkers to assist diagnosis of Parkinson’s disease (PD). Our aim was to investigate PD related iron changes in the substantia nigra pars compacta (SNpc) as defined by neuromelanin-sensitive MR contrast. METHODS: Thirty-nine PD participants and 33 hea...

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Bibliografiska uppgifter
I publikationen:Neuroimage Clin
Huvudupphovsmän: He, Naying, Langley, Jason, Huddleston, Daniel E., Chen, Shengdi, Huang, Pei, Ling, Huawei, Yan, Fuhua, Hu, Xiaoping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479276/
https://ncbi.nlm.nih.gov/pubmed/32889398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102391
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