PS3-35: MRI Detection of Substantia Nigra Degeneration in Parkinson’s Disease: Developing a Candidate Biomarker

BACKGROUND/AIMS: The substantia nigra (SN) selectively degenerates in Parkinson’s disease (PD). Prior MRI studies of SN have used manual segmentation to make quantitative measurements, an approach with inherently limited accuracy. Here we used an in-house optimized neuromelanin MRI (NM-MRI) protocol...

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Bibliographic Details
Main Authors: Huddleston, Daniel, Chen, Xiangchuan, Langley, Jason, Hu, Xiaoping
Format: Artigo
Language:Inglês
Published: Marshfield Clinic 2013
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Selected Abstracts-HMORN 2013: Chronic Conditions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3121/cmr.2013.1176.ps3-35
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