Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing

Despite evidence of a substantial genetic component, the genetic factors that underlie longevity in humans remain to be identified. Previous genome-wide linkage and association studies have not found strong evidence for the contribution of common variants besides the APOE gene, suggesting the role o...

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Main Authors: Han, Jeehae, Ryu, Seungjin, Moskowitz, David M, Rothenberg, Devorah, Leahy, Daniel J., Atzmon, Gil, Barzilai, Nir, Suh, Yousin
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787996/
https://ncbi.nlm.nih.gov/pubmed/23376243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2013.01.005
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