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Genetic landscape of APOE in human longevity revealed by high-throughput sequencing
Apolipoprotein E (APOE) gene has been the most replicated longevity-associated gene in humans. Two common APOE alleles are either significantly depleted (ε4 allele) or enriched (ε2 allele) in long-lived individuals as compared to controls. We performed high-throughput sequencing analysis of exons an...
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| 出版年: | Mech Ageing Dev |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4818712/ https://ncbi.nlm.nih.gov/pubmed/26930295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.02.010 |
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