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Functionally significant insulin-like growth factor I receptor mutations in centenarians
Rather than being a passive, haphazard process of wear and tear, lifespan can be modulated actively by components of the insulin/insulin-like growth factor I (IGFI) pathway in laboratory animals. Complete or partial loss-of-function mutations in genes encoding components of the insulin/IGFI pathway...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265137/ https://ncbi.nlm.nih.gov/pubmed/18316725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705467105 |
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