Role of Focal Adhesion Kinase in Regulating YB–1–Mediated Paclitaxel Resistance in Ovarian Cancer

BACKGROUND: We previously found focal adhesion kinase (FAK) inhibition sensitizes ovarian cancer to taxanes; however, the mechanisms are not well understood. METHODS: We characterized the biologic response of taxane-resistant and taxane-sensitive ovarian cancer models to a novel FAK inhibitor (VS-60...

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Detalhes bibliográficos
Main Authors: Kang, Yu, Hu, Wei, Ivan, Cristina, Dalton, Heather J., Miyake, Takahito, Pecot, Chad V., Zand, Behrouz, Liu, Tao, Huang, Jie, Jennings, Nicholas B., Rupaimoole, Rajesha, Taylor, Morgan, Pradeep, Sunila, Wu, Sherry Y., Lu, Chunhua, Wen, Yunfei, Huang, Jianfei, Liu, Jinsong, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787907/
https://ncbi.nlm.nih.gov/pubmed/24062525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt210
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