Role of Focal Adhesion Kinase in Regulating YB–1–Mediated Paclitaxel Resistance in Ovarian Cancer

BACKGROUND: We previously found focal adhesion kinase (FAK) inhibition sensitizes ovarian cancer to taxanes; however, the mechanisms are not well understood. METHODS: We characterized the biologic response of taxane-resistant and taxane-sensitive ovarian cancer models to a novel FAK inhibitor (VS-60...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kang, Yu, Hu, Wei, Ivan, Cristina, Dalton, Heather J., Miyake, Takahito, Pecot, Chad V., Zand, Behrouz, Liu, Tao, Huang, Jie, Jennings, Nicholas B., Rupaimoole, Rajesha, Taylor, Morgan, Pradeep, Sunila, Wu, Sherry Y., Lu, Chunhua, Wen, Yunfei, Huang, Jianfei, Liu, Jinsong, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787907/
https://ncbi.nlm.nih.gov/pubmed/24062525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt210
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares