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The VHL tumor suppressor in development and disease: Functional studies in mice by conditional gene targeting

The von Hippel–Lindau tumor suppressor pVHL plays a critical role in the pathogenesis of familial and sporadic clear cell carcinomas of the kidney and hemangioblastomas of the retina and central nervous system. pVHL targets the oxygen sensitive alpha subunit of hypoxia-inducible factor (HIF) for pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Haase, Volker H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787877/
https://ncbi.nlm.nih.gov/pubmed/15908240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2005.03.006
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