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The VHL tumor suppressor in development and disease: Functional studies in mice by conditional gene targeting

The von Hippel–Lindau tumor suppressor pVHL plays a critical role in the pathogenesis of familial and sporadic clear cell carcinomas of the kidney and hemangioblastomas of the retina and central nervous system. pVHL targets the oxygen sensitive alpha subunit of hypoxia-inducible factor (HIF) for pro...

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Bibliografski detalji
Glavni autor: Haase, Volker H.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787877/
https://ncbi.nlm.nih.gov/pubmed/15908240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2005.03.006
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