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Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes

Deregulation of calcium has been implicated in neurodegenerative diseases, including Alzheimer’s disease (AD). Previously, we showed that saturated free-fatty acid, palmitate, causes AD-like changes in primary cortical neurons mediated by astrocytes. However, the molecular mechanisms by which condit...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Li, Martin, Rebecca, Kohler, Garrett, Chan, Christina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787872/
https://ncbi.nlm.nih.gov/pubmed/23968646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.08.004
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