Indirect Regulation of Presenilins in CREB-mediated Transcription

Presenilins are essential for synaptic function, memory formation, and neuronal survival. Previously, we reported that expression of cAMP response element-binding protein (CREB) target genes is reduced in the cerebral cortex of presenilin (PS) conditional double knock-out (cDKO) mice. To determine w...

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Detalhes bibliográficos
Main Authors: Watanabe, Hirotaka, Smith, Miriam J., Heilig, Elizabeth, Beglopoulos, Vassilios, Kelleher, Raymond J., Shen, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679472/
https://ncbi.nlm.nih.gov/pubmed/19289467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809168200
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