Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes

Direct lineage reprogramming induces dramatic shifts in cellular identity, employing poorly understood mechanisms. Recently, we demonstrated that expression of Neurog2 or Ascl1 in postnatal mouse astrocytes generates glutamatergic or GABAergic neurons. Here, we take advantage of this model to study...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Masserdotti, Giacomo, Gillotin, Sébastien, Sutor, Bernd, Drechsel, Daniela, Irmler, Martin, Jørgensen, Helle F., Sass, Steffen, Theis, Fabian J., Beckers, Johannes, Berninger, Benedikt, Guillemot, François, Götz, Magdalena
Format: Artigo
Langue:Inglês
Publié: Cell Press 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509553/
https://ncbi.nlm.nih.gov/pubmed/26119235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.05.014
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires