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Synthetic Chondramide A Analogues Stabilize Filamentous Actin and Block Invasion by Toxoplasma gondii
[Image: see text] Apicomplexan parasites such as Toxoplasma gondii rely on actin-based motility to cross biological barriers and invade host cells. Key structural and biochemical differences in host and parasite actins make this an attractive target for small-molecule inhibitors. Here we took advant...
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| Główni autorzy: | , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American
Chemical Society and American
Society of Pharmacognosy
2013
|
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787807/ https://ncbi.nlm.nih.gov/pubmed/24020843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400196w |
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