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GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis

Certain thermoreceptor neurons are sensitive to tiny thermal fluctuations (0.01°C or less) and maintain their sensitivity across a wide range of ambient temperatures through a process of adaptation, but understanding of the biochemical basis for this performance is rudimentary. Prior studies of the...

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Detalhes bibliográficos
Main Authors: Wang, Dong, O’Halloran, Damien, Goodman, Miriam B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787776/
https://ncbi.nlm.nih.gov/pubmed/24081984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310959
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