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Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal

The adaptive immune response begins when CD4+ T cells recognize antigenic peptides bound to class II molecules of the Major Histocompatibility Complex (MHCII). The interaction between peptides and MHCII has been historically interpreted as a rigid docking event. However, this model has been challeng...

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Autor principal: Ferrante, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787305/
https://ncbi.nlm.nih.gov/pubmed/24101920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00308
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