A carregar...

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

UPF1 is a DNA/RNA helicase with essential roles in nonsense-mediated mRNA decay (NMD) and embryonic development. How UPF1 regulates target abundance and the relationship between NMD and embryogenesis are not well understood. To explore how NMD shapes the embryonic transcriptome, we integrated genome...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hurt, Jessica A., Robertson, Alex D., Burge, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787261/
https://ncbi.nlm.nih.gov/pubmed/23766421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157354.113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!