PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

Glioblastoma multiforme is an aggressive and incurable type of brain tumor. A subset of undifferentiated glioblastoma cells, known as glioblastoma tumor initiating cells (GTICs), has an essential role in the malignancy of this disease and also appears to mediate resistance to radiation therapy and c...

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Hlavní autoři: Gont, Alexander, Hanson, Jennifer E L, Lavictoire, Sylvie J, Parolin, Doris A E, Daneshmand, Manijeh, Restall, Ian J, Soucie, Mathieu, Nicholas, Garth, Woulfe, John, Kassam, Amin, Da Silva, Vasco F, Lorimer, Ian AJ
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2013
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787156/
https://ncbi.nlm.nih.gov/pubmed/23907540
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