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Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS deficient ApoE ko mice

OBJECTIVE: Hypercholesterolemia is associated with decreased vascular nitric oxide bioavailability and deletion of endothelial nitric oxide synthase (eNOS) markedly accelerates atherosclerosis development in apolipoprotein E knockout (apoE ko) mice. The current study tests whether atheroprotection p...

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Bibliografske podrobnosti
Main Authors: Kuhlencordt, Peter J., Padmapriya, P., Rützel, S., Schödel, J., Hu, K., Schäfer, A., Huang, P.L., Ertl, G., Bauersachs, J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786446/
https://ncbi.nlm.nih.gov/pubmed/18479686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2008.03.021
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