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Staurosporine is chemoprotective by inducing G(1) arrest in a Chk1- and pRb-dependent manner
Chemotherapeutic agents have been the mainstay of cancer therapy for years. However, their effectiveness has been limited by toxicities they impart on normal cells. Staurosporine (ST) has been shown to arrest normal, but not breast cancer, cells in G(1). Therefore, ST may become a chemoprotective ag...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786379/ https://ncbi.nlm.nih.gov/pubmed/23722650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt186 |
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