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Staurosporine is chemoprotective by inducing G(1) arrest in a Chk1- and pRb-dependent manner
Chemotherapeutic agents have been the mainstay of cancer therapy for years. However, their effectiveness has been limited by toxicities they impart on normal cells. Staurosporine (ST) has been shown to arrest normal, but not breast cancer, cells in G(1). Therefore, ST may become a chemoprotective ag...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786379/ https://ncbi.nlm.nih.gov/pubmed/23722650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt186 |
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