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Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer
Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences are poorly understood. We report an analysis of β-dystroglycan in prostate cancer in human tissue samples and in LNCaP cells in vitro. There is progressive loss of β-dystroglycan immunoreactivity from basal and la...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786294/ https://ncbi.nlm.nih.gov/pubmed/24077328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02792 |
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