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γ‐Secretase Dependent Nuclear Targeting of Dystroglycan

Dystroglycan is frequently lost in adenocarcinoma. α‐dystroglycan is known to become hypoglycosylated due to transcriptional silencing of LARGE, whereas β‐dystroglycan is proteolytically cleaved and degraded. The mechanism and proteases involved in the cleavage events affecting β‐dystroglycan are po...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Leocadio, Daniel, Mitchell, Andrew, Winder, Steve J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982099/
https://ncbi.nlm.nih.gov/pubmed/26990187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25537
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