Nuclear mTOR acts as a transcriptional integrator of the androgen signaling pathway in prostate cancer

Androgen receptor (AR) signaling reprograms cellular metabolism to support prostate cancer (PCa) growth and survival. Another key regulator of cellular metabolism is mTOR, a kinase found in diverse protein complexes and cellular localizations, including the nucleus. However, whether nuclear mTOR pla...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Audet-Walsh, Étienne, Dufour, Catherine R., Yee, Tracey, Zouanat, Fatima Z., Yan, Ming, Kalloghlian, Georges, Vernier, Mathieu, Caron, Maxime, Bourque, Guillaume, Scarlata, Eleonora, Hamel, Lucie, Brimo, Fadi, Aprikian, Armen G., Lapointe, Jacques, Chevalier, Simone, Giguère, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558925/
https://ncbi.nlm.nih.gov/pubmed/28724614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299958.117
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