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T Cell–Independent Rescue of B Lymphocytes from Peripheral Immune Tolerance

Autoimmunity arises when immune tolerance to specific self-antigens is broken. The mechanisms leading to such a failure remain poorly understood. One hypothesis proposes that infectious agents or antigens can break B or T lymphocyte self-tolerance by expressing epitopes that mimic self. Using a tran...

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Detalhes bibliográficos
Main Authors: Kouskoff, Valerie, Lacaud, Georges, Nemazee, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786169/
https://ncbi.nlm.nih.gov/pubmed/10741972
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