Molecular Analysis of the Cyclic AMP-Dependent Protein Kinase A (PKA) Regulatory Subunit 1A (PRKAR1A) Gene in Patients with Carney Complex and Primary Pigmented Nodular Adrenocortical Disease (PPNAD) Reveals Novel Mutations and Clues For Pathophysiology: Augmented PKA Signaling is Associated with Adrenal Tumorigenesis in PPNAD

Ítems similars

• mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD)
  per: de Joussineau, Cyrille, et al.
  Publicat: (2014)
• Detection of somatic β-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD)
  per: Tadjine, Mimi, et al.
  Publicat: (2008)
• PRKAR1A, one of the Carney complex genes, and its locus (17q22-24) are rarely altered in pituitary tumours outside the Carney complex
  per: Sandrini, F, et al.
  Publicat: (2002)
• Differential Role of PKA Catalytic Subunits in Mediating Phenotypes Caused by Knockout of the Carney Complex Gene Prkar1a
  per: Yin, Zhirong, et al.
  Publicat: (2011)
• A Large Family with Carney Complex Caused by the S147G PRKAR1A Mutation Shows a Unique Spectrum of Disease Including Adrenocortical Cancer
  per: Anselmo, João, et al.
  Publicat: (2012)