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Using Antiubiquitin Antibodies to Probe the Ubiquitination State Within rhTRIM5α Cytoplasmic Bodies

The first line of defense protecting rhesus macaques from HIV-1 is the restriction factor rhTRIM5α, which recognizes the capsid core of the virus early after entry and normally blocks infection prior to reverse transcription. Cytoplasmic bodies containing rhTRIM5α have been implicated in the ubiquit...

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Detalhes bibliográficos
Main Authors: Danielson, Cindy M., Hope, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785812/
https://ncbi.nlm.nih.gov/pubmed/23799296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2013.0029
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