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The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

Aims: We asked whether the neuroprotective effect of cholinergic microglial stimulation during an ischemic event acts via a mechanism involving the activation of nuclear factor erythroid-2-related factor 2 (Nrf2) and/or the expression of its target cytoprotective gene, heme oxygenase-1 (HO-1). Speci...

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Hlavní autoři: Parada, Esther, Egea, Javier, Buendia, Izaskun, Negredo, Pilar, Cunha, Ana C., Cardoso, Silvia, Soares, Miguel P., López, Manuela G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785807/
https://ncbi.nlm.nih.gov/pubmed/23311871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4671
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