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Heme oxygenase-2 is neuroprotective in cerebral ischemia.

Heme oxygenase (HO) is believed to be a potent antioxidant enzyme in the nervous system; it degrades heme from heme-containing proteins, giving rise to carbon monoxide, iron, and biliverdin, which is rapidly reduced to bilirubin. The first identified isoform of the enzyme, HO1, is an inducible heat-...

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Autores principales: Doré, S., Sampei, K., Goto, S., Alkayed, N. J., Guastella, D., Blackshaw, S., Gallagher, M., Traystman, R. J., Hurn, P. D., Koehler, R. C., Snyder, S. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Feinstein Institute for Medical Research 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230472/
https://ncbi.nlm.nih.gov/pubmed/10602774
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