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Semisynthetic K(+) channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state
C-type inactivation of K(+) channels plays a key role in modulating cellular excitability. During C-type inactivation, the selectivity filter of a K(+) channel changes conformation from a conductive to a nonconductive state. Crystal structures of the KcsA channel determined at low K(+) or in the ope...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785774/ https://ncbi.nlm.nih.gov/pubmed/24019483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308699110 |
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