Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner

Pancreatic stellate cells (PSC) are a subset of pancreatic cancer-associated fibroblasts. These cells provide prosurvival signals to tumors; however, little is known regarding their interactions with immune cells within the tumor microenvironment. We hypothesized that factors produced by human PSC c...

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Main Authors: Mace, Thomas A., Ameen, Zeenath, Collins, Amy, Wojcik, Sylwia, Mair, Markus, Young, Gregory S., Fuchs, James R., Eubank, Tim D., Frankel, Wendy L., Bekaii-Saab, Tanios, Bloomston, Mark, Lesinski, Gregory B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785672/
https://ncbi.nlm.nih.gov/pubmed/23514705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4601
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