Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy

Interferon-alpha (IFN-α) promotes anti-tumor immunity through its actions on immune cells. We hypothesized that elevated percentages of myeloid-derived suppressor cells (MDSC) and increased pro-inflammatory cytokines in peripheral blood would be associated with impaired response to IFN-α in patients...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mundy-Bosse, Bethany L., Young, Gregory S., Bauer, Todd, Binkley, Elaine, Bloomston, Mark, Bill, Matthew A., Bekaii-Saab, Tanios, Carson, William E., Lesinski, Gregory B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2011
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521517/
https://ncbi.nlm.nih.gov/pubmed/21604071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1029-z
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