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Modeling the Conformational Changes Underlying Channel Opening in CFTR
Mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator protein (CFTR) cause cystic fibrosis (CF), the most common life-shortening genetic disease among Caucasians. Although general features of the structure of CFTR have been predicted from homology models, the conform...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785483/ https://ncbi.nlm.nih.gov/pubmed/24086355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074574 |
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