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Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase
Bacillus stearothermophilus PFK (BsPFK) is a homotetramer that is allosterically inhibited by phosphoenolpyruvate (PEP), which binds along one dimer-dimer interface. The substrate, fructose 6-phosphate (Fru-6-P), binds along the other dimer-dimer interface. Evans et al., observed that the inhibitor,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785328/ https://ncbi.nlm.nih.gov/pubmed/23859543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4002503 |
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