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The Effects of Protein-Ligand Associations on the Subunit Interactions of Phosphofructokinase from B. stearothermophilus

Differences between the crystal structures of inhibitor-bound and uninihibited forms of phosphofructokinase (PFK) from B. stearothermophilus have led to a structural model for allosteric inhibition by phosphenolpyruvate (PEP) wherein a dimer-dimer interface within the tetrameric enzyme undergoes a q...

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Autors principals: Quinlan, R. Jason, Reinhart, Gregory D.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516970/
https://ncbi.nlm.nih.gov/pubmed/16981693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0608921
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