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Retinoic Acid Receptor α Is Required for Synchronization of Spermatogenic Cycles and Its Absence Results in Progressive Breakdown of the Spermatogenic Process

Targeted mutagenesis of the retinoic acid receptor α (RARα) gene has revealed its essential role in spermatogenesis. Although cells in all stages of spermatogenesis were detected in RARα(−/−) testes, there was an increase in degenerating pachytene spermatocytes and a temporary developmental arrest i...

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Detalhes bibliográficos
Main Authors: Chung, Sanny S.W., Sung, Wengkong, Wang, Xiangyuan, Wolgemuth, Debra J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785309/
https://ncbi.nlm.nih.gov/pubmed/15254909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20083
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