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Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment

It has been suggested that the concentrations of tamoxifen and its demethylated metabolites increase with age. We measured the serum concentrations of the active tamoxifen metabolites, 4OHtamoxifen (4OHtam), 4-hydroxy-N-desmethyltamoxifen (4OHNDtam, Endoxifen), tamoxifen and its demethylated metabol...

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Detalhes bibliográficos
Main Authors: Lien, Ernst A., Søiland, Håvard, Lundgren, Steinar, Aas, Turid, Steen, Vidar M., Mellgren, Gunnar, Gjerde, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785179/
https://ncbi.nlm.nih.gov/pubmed/23996142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2677-9
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