Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

BACKGROUND: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement of concentrations of active tamoxifen metabolites in serum may be a more biolo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res
Prif Awduron: Helland, Thomas, Henne, Nina, Bifulco, Ersilia, Naume, Bjørn, Borgen, Elin, Kristensen, Vessela N., Kvaløy, Jan T., Lash, Timothy L., Alnæs, Grethe I. G., van Schaik, Ron H., Janssen, Emiel A. M., Hustad, Steinar, Lien, Ernst A., Mellgren, Gunnar, Søiland, Håvard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706168/
https://ncbi.nlm.nih.gov/pubmed/29183390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0916-4
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