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The transcription factor Engrailed-2 guides retinal axons
Engrailed-2 (En-2), a homeodomain transcription factor, is expressed in a caudal-to-rostral gradient in the developing mid-brain, where it has an instructive role in patterning the optic tectum—the target of topographic retinal input(1,2). In addition to its well-known role in regulating gene expres...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785142/ https://ncbi.nlm.nih.gov/pubmed/16267555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04110 |
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