Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo

Engrailed transcription factors regulate the expression of guidance cues that pattern retinal axon terminals in the dorsal midbrain. They also act directly to guide axon growth in vitro. We show here that an extracellular En gradient exists in the tectum along the anterior-posterior axis. Neutralizi...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Wizenmann, Andrea, Brunet, Isabelle, Lam, Joyce, Sonnier, Laure, Beurdeley, Marine, Zarbalis, Konstantinos, Weisenhorn-Vogt, Daniela, Weinl, Christine, Dwivedy, Asha, Joliot, Alain, Wurst, Wolfgang, Holt, Christine, Prochiantz, Alain
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603356/
https://ncbi.nlm.nih.gov/pubmed/19914184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.09.018
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