Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease

Alloreactive donor T cells against host minor histocompatibility antigens (mHAs) cause graft-versus-host disease (GVHD) after marrow transplantation from HLA-identical siblings. We sought to identify and expand regulatory CD4 T cells (Tregs) specific for human mHAs in numbers and potency adequate fo...

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Bibliographic Details
Main Authors: Veerapathran, Anandharaman, Pidala, Joseph, Beato, Francisca, Betts, Brian, Kim, Jongphil, Turner, Joel G., Hellerstein, Marc K., Yu, Xue-Zhong, Janssen, William, Anasetti, Claudio
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785121/
https://ncbi.nlm.nih.gov/pubmed/23908471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492397
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