Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

Neutralizing and non-neutralizing antibodies to linear epitopes on HIV-1 envelope glycoproteins have potential to mediate antiviral effector functions that could be beneficial to vaccine-induced protection. Here, plasma IgG responses were assessed in three HIV-1 gp120 vaccine efficacy trials (RV144,...

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Main Authors: Gottardo, Raphael, Bailer, Robert T., Korber, Bette T., Gnanakaran, S., Phillips, Joshua, Shen, Xiaoying, Tomaras, Georgia D., Turk, Ellen, Imholte, Gregory, Eckler, Larry, Wenschuh, Holger, Zerweck, Johannes, Greene, Kelli, Gao, Hongmei, Berman, Phillip W., Francis, Donald, Sinangil, Faruk, Lee, Carter, Nitayaphan, Sorachai, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Tartaglia, James, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Zolla-Pazner, Susan, Haynes, Barton F., Mascola, John R., Self, Steve, Gilbert, Peter, Montefiori, David C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784573/
https://ncbi.nlm.nih.gov/pubmed/24086607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075665
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