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Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
Aggregation of tau protein in the brain is associated with a class of neurodegenerative diseases known as tauopathies. FK506 binding protein 51 kDa (FKBP51, encoded by FKBP5) forms a mature chaperone complex with Hsp90 that prevents tau degradation. In this study, we have shown that tau levels are r...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society for Clinical Investigation
2013
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784538/ https://ncbi.nlm.nih.gov/pubmed/23999428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69003 |
| ট্যাগগুলো: |
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