Retinal angiogenesis suppression through small molecule activation of p53

Neovascular age-related macular degeneration is a leading cause of irreversible vision loss in the Western world. Cytokine-targeted therapies (such as anti-vascular endothelial growth factor) are effective in treating pathologic ocular angiogenesis, but have not led to a durable effect and often req...

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Main Authors: Chavala, Sai H., Kim, Younghee, Tudisco, Laura, Cicatiello, Valeria, Milde, Till, Kerur, Nagaraj, Claros, Nidia, Yanni, Susan, Guaiquil, Victor H., Hauswirth, William W., Penn, John S., Rafii, Shahin, De Falco, Sandro, Lee, Thomas C., Ambati, Jayakrishna
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784529/
https://ncbi.nlm.nih.gov/pubmed/24018558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67315
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