Retinal angiogenesis suppression through small molecule activation of p53

Neovascular age-related macular degeneration is a leading cause of irreversible vision loss in the Western world. Cytokine-targeted therapies (such as anti-vascular endothelial growth factor) are effective in treating pathologic ocular angiogenesis, but have not led to a durable effect and often req...

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Detalhes bibliográficos
Main Authors: Chavala, Sai H., Kim, Younghee, Tudisco, Laura, Cicatiello, Valeria, Milde, Till, Kerur, Nagaraj, Claros, Nidia, Yanni, Susan, Guaiquil, Victor H., Hauswirth, William W., Penn, John S., Rafii, Shahin, De Falco, Sandro, Lee, Thomas C., Ambati, Jayakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784529/
https://ncbi.nlm.nih.gov/pubmed/24018558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67315
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