Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease

Single base substitutions constitute the most frequent type of human gene mutation and are a leading cause of cancer and inherited disease. These alterations occur non-randomly in DNA, being strongly influenced by the local nucleotide sequence context. However, the molecular mechanisms underlying su...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bacolla, Albino, Temiz, Nuri A., Yi, Ming, Ivanic, Joseph, Cer, Regina Z., Donohue, Duncan E., Ball, Edward V., Mudunuri, Uma S., Wang, Guliang, Jain, Aklank, Volfovsky, Natalia, Luke, Brian T., Stephens, Robert M., Cooper, David N., Collins, Jack R., Vasquez, Karen M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784513/
https://ncbi.nlm.nih.gov/pubmed/24086153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003816
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker