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Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease
Single base substitutions constitute the most frequent type of human gene mutation and are a leading cause of cancer and inherited disease. These alterations occur non-randomly in DNA, being strongly influenced by the local nucleotide sequence context. However, the molecular mechanisms underlying su...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784513/ https://ncbi.nlm.nih.gov/pubmed/24086153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003816 |
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